Catch a bus from San Jose to Quepos, and then from Quepos to Manuel Antonio. Schedules vary, so it’s best to inquire directly with the bus company at 2777-0318. From Quepos to Manuel Antonio, buses leave every 30 minutes.
From San Jose, take the Panamerican Highway #1 North towards San Ramon / Puntarenas. Keep driving on the highway north until the first main exit on your right which has a sign that says: Atenas, Orotina, Jaco, Quepos. Take that exit and turn left immediately at the stop sign. Crossover the highway and continue towards Atenas, follow the signs to Jaco and Quepos / Manuel Antonio National Park.
Rent a car:
Driving yourself to Manuel Antonio and Quepos is easy. For the best service companies and rates, please fill out our car rental form, and we will find you some good options.
There are short local flights from San Jose and Liberia to Quepos. Nature Air offers comfortable flights to Quepos and many other destinations in Costa Rica.
Interbus provides an efficient and economic shuttle service from the Central Valley (San Jose) to Manuel Antonio or Quepos, and many other destinations on the Pacific Coast of Costa Rica. A reservation is needed 72-hour in advance!